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Major product and polymer categories and associated
sterilisation applications
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Polymers
Healthcare products |
Some applicable
sterilisation processes |
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Thermoplastics |
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Acrylonitrile
butadiene styrene (ABS)
IV spikes,
luer, Y-connector, roller clamp, filter cases,
blood dialysis units |
Limited steam, EO, radiation, H2O2,
ozone |
|
Acetals (Delrin)
Stopcocks, structural keel for a prosthetic
device, engineering plastic, others |
Dry heat, EO |
|
Acrylics
Tubing connectors, needle adapters, blood set
components, contact lenses, lays |
EO, limited radiation,
chlorine dioxide,
H2O2 |
|
Parylene-poly-xylene
Coating used in catheters, stents, needles,
cardiac assist devices, prosthetics, cannulae |
Steam, dry heat, EO,
radiation,
H2O2,
ozone |
|
Poly
etheretheketone (PEEK)
Cardiovascular, orthopaedicand dental implants and
tubing |
Dry heat, EO, steam,
radiation,
H2O2 |
|
Polycarbonate
Blood sets (oxygenators), tubing connectors,
injection sites, valve occluders, general
structura, syringes, rigid containers, cases,
safety syringes, haemodialysers, cardiotomy
trocars, reservoirs, surgical instruments,
profusion devices, blood centrifuge bowls,
stopcocks, needles syringes, drug delivery
devices, IV connectors, part of positive
expiratory pressure (PEP) system. |
Steam (watch out for
vacuums), limited dry heat, EO, limited radiation,
H2O2,
ozone |
|
Polyethylene vinyl
acetate (EVA)
Packaging, hydroged, gloves, drug delivery, silms |
EO, radiation |
|
Polyglycolide (PGA),
polyactide (PLA) includes copolymers,
polycaprolactone (PCL)
Ophthalmology lenses and contact lenses, grout for
artificial joints, orthopaedics, bone cement,
cranioplasty, neurosurgery, membrane oxygenators,
corneal prosthesis, contact lenses. |
Limited chlorine
dioxide, EO, limited radiation,
H2O2 |
|
Polyolefins,
polyethylene (LDPE, LLDPE, HDPE, UHMWPE) and
polypropylene (PP) also PP/PE copolymers
Films, tubing and containers for packaging
applications, container-sterile water, urine bags,
blood oxygenators-polypropylene membrane and
hollow fibres, syringes, dialysis membranes, heart
valve occluders, sutures, catheters, protective
tubes, hip joints, packaging, PP contact lens
casting cup, part of positive expiratory pressure
(PEP) system. |
EO, limited radiation
(on polypropylene), limited steam (PP and some
high density polyethylene), low temperature dry
heat limited (polypropylene),
H2O2 |
|
Polyolefin
copolymers (PE/PP, PPCO)
Parenteral solution containers |
Steam, EO,
H2O2 |
|
Polystyrene
Sputurn cups, containers, tubes, petri dishes. |
EO radiation,
H2O2 |
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Polyurethane
IV containers, enteral feeding tubes, blood pumps,
artificial heart ventricles, catheters and tubing,
leads, catheters and components, valves, needless
syringes, drug delivery devices, diagnostic
components, lipid resistant stopcocks, vials,
connetors, components connected to PVC tubing,
surgical instruments, facial protheses, cuffs,
transdermal patches, drug delivery devices,
angioplasty balloons, blood device interfaces. |
EO, radiation, limited
dry heat, steam,
H2O2
|
|
Polyvinyl chloride
IV therapy: glucose solutions and saline
solutions, drug mixtures, nutrients, flexible PVC
containers collection, storage and administration
of blood and blood components (blood bags), tubing
and catheters, oxygenators and dialysers, IV drip
chambers, gastrointestinal grafts, shrink tubing,
urine bags, endotracheal tubes, drip chambers,
blood vessels, gastrointestinal grafts, hearing
aid components. |
Steam, limited dry
heat, EO, limited radiation,
H2O2
|
|
Styrene -
acrylonitriles (SAN)
Dialysis, intravenous connectors |
EO, radiation,
H2O2 |
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Thermoset Polymers |
|
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Silicone
Extruded tubing - small tubing, foley catheters
for urinary drains, catheters used for infusion of
IV solutions required for parenteral nutrition,
silicone rubber membranes in blood oxygenators,
nasogastric tubing, eustachian tube prosthetics
(ear parts), other prosthetics (mammary glands,
heart components, joints), reconstructive surgery,
ear, bone and joints. |
Dry heat, limited
steam (may not penetrate), EO (leaves residues),
limited radiation (may crosslink),
H2O2,
ozone |
Source: “Sterilisation of Polymer
Healthcare Products” by Wayne Rogers, Published by: Rapra
Technology
Ltd, U.K.
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